Mary K. Crow, MD

Dr. Crow is Associate Chief, Division of Rheumatology and Director of Rheumatology Research at Hospital for Special Surgery. She combines basic and translational research on the mechanisms that underlie systemic autoimmune diseases with active participation in the clinical and academic programs of the hospital and Weill Medical College of Cornell University. Patients with systemic lupus erythematosus, rheumatoid arthritis and scleroderma have made important contributions to the understanding of those diseases through their participation in Dr. Crow’s research. Dr. Crow serves as Co-Director of the Mary Kirkland Center for Lupus Research and Director of the Autoimmunity and Inflammation Research Program at Hospital for Special Surgery.

Appointments

Attending Physician, Hospital for Special Surgery

Attending Physician, New York Presbyterian Hospital

Professor of Medicine, Weill Medical College of Cornell University

Senior Scientist, Hospital for Special Surgery


Specialty
Rheumatology

Internal Medicine


Certification

Internal Medicine, Rheumatology


State Licensure
New York

Education

MD, 1978, Cornell University Medical College, New York


Internship

New York Hospital, Internal Medicine, New York, 1978-1979


Residency

New York Hospital, Internal Medicine, New York, 1979-1981


Fellowship

Rockefeller University, Immunology Research, New York, 1981-1984

Hospital for Special Surgery, Rheumatology, New York, 1981-1984


Mary K. Crow, MD is the author of the following articles on HSS.edu:
For Professionals
Special Expertise

Systemic lupus erythematosus

Rheumatoid arthritis


Research Interests
Mechanisms of autoimmune disease, Genomic triggers of autoimmunity, Systemic lupus erythematosus, Rheumatoid arthritis, Scleroderma

Awards

Arthritis Hero, Arthritis Foundation, 2001

Benjamin M. Rosen Chair in Autoimmunity and Inflammation Research, 2002


Affiliations

American College of Rheumatology, President-Elect

Member, Medical Advisory Committee, The S.L.E. Foundation, Inc.


Selected Publications

Chernysheva AD, Kirou KA, Crow MK. T cell proliferation induced by autologous non-T cells is a response to apoptotic cells processed by dendritic cells. J Immunol 169:1241-1250, 2002.

Roman MJ, Shanker B-A, Davis A, Lockshin MD, Sammaritano L, Simantov R, Crow MK, Schwartz JE, Paget SA, Devereux RB, Salmon JE. Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosus. N Engl J Med 349:2399-406, 2003.

Crow MK, Kirou KA, Wohlgemuth J. Microarray analysis of interferon-regulated genes in SLE. Autoimmunity 36:481-490, 2003.

Crow MK. Type I interferon and autoimmune disease. Autoimmunity 36:445-446, 2003.

Crow MK: Costimulatory molecules and T cell-B cell interactions. Rheum Dis Clin N Amer, 30:175-191, 2003.

Crow MK, Kirou KA. Interferon-alpha in systemic lupus erythematosus. Curr Opin Rheum, 16:541-547, 2004.

Liu S, Cerutti A, Casali P, Crow MK. Ongoing immunoglobulin class switch DNA recombination in lupus B cells: analysis of switch regulatory sequences. Autoimmunity, 37:431-443, 2004.

Kirou KA, Lee C, George S, Louca K, Papagiannis IG, Peterson MGE, Ly N, Woodward RN, Fry KE, Lau A Y-H, Prentice JG, Wohlgemuth JG, Crow MK. Coordinate overexpression of interferon-alpha-induced genes in systemic lupus erythematosus. Arthritis Rheum, 50:3958-67, 2004.

Kirou KA, Lee C, George S, Louca K, Peterson MGE, Crow MK. Interferon-alpha pathway activation identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease. Arthritis Rheum, 52:1491-503, 2005.

Roman MJ, Devereux RB, Schwartz JE, Lockshin MD, Paget SA, Davis A, Crow MK, Sammaritano L, Levine DM, Shankar B-A, Moeller E, Salmon JE. Arterial Stiffness in Chronic Inflammatory Diseases. Hypertension, 46:194-9, 2005.


For more publications, please see the PubMed listing.

Clinical Trials
Specialized Centers
Mary Kirkland Center for Lupus Research