Jane E. Salmon, MD
Dr. Jane Salmon is Professor of Medicine and Professor of Obstetrics and Gynecology at Weill Medical College and the Collette Kean Research Professor at Hospital for Special Surgery.
Dr. Salmon graduated magna cum laude from New York University and earned a medical degree in 1978 from the College of Physicians and Surgeons of Columbia University, where she was the first woman enrolled in their Medical Scientist Training Program. She completed training in internal medicine at The New York Hospital and in rheumatology at Hospital for Special Surgery, and has been an HSS faculty member since 1983. Dr. Salmon is on the Board of Directors of the American College of Rheumatology, Councilor of the Clinical Immunology Society, and co-editor of Arthritis and Rheumatism. She serves on the NIH Advisory Boards for the North American Rheumatoid Arthritis Consortium, Lupus Multiplex Registry, Consortium for the Longitudinal Evaluation of African-Americans with Early RA. At HSS, she is a co-Director of the Mary Kirkland Center for Lupus Research, Director of the FOCIS Center of Excellence, and Director of the Lupus Registry and Repository.
Dr. Salmon’s research has focused on elucidating mechanisms of tissue injury in lupus and other autoimmune diseases. Her basic and clinical studies have expanded our understanding of pregnancy loss and organ damage in SLE and the determinants of disease outcome in lupus patients with nephritis, pregnancy, and cardiovascular disease.
Appointments
Attending Physician, Hospital for Special Surgery
Collette Kean Research Chair, Hospital for Special Surgery
Senior Scientist, Hospital for Special Surgery
Co-Director, Mary Kirkland Center for Lupus Research, Hospital for Special Surgery
Director of the Lupus Registry and Repository, Hospital for Special Surgery
Professor of Medicine, Weill Medical College of Cornell University
Professor of Medicine in Ostetrics and Gynecology, Weill Medical College of Cornell University
Professor, Graduate Program in Immunology, Weill Graduate School of Medical Sciences of Cornell University
Specialty
Rheumatology
Internal Medicine
Certification
Internal Medicine
Rheumatology
State Licensure
New York
Education
MD, Columbia University College of Physicians and Surgeons, New York, US
Residency
The New York Hospital, New York, US
Fellowship
Hospital for Special Surgery, Fellow in Rheumatic Diseases, US
Jane E. Salmon, MD is the author of the following articles on HSS.edu:
For Professionals
Special Expertise
Systemic lupus erythematosus
Antiphospholipid syndrome
Rheumatoid arthritis
Research Interests
Systemic lupus erythematosus
Antiphospholipid syndrome
Pregnancy in autoimmune patients
Cardiovascular disease in autoimmune patients
Awards
Edmund L. Dubois, MD, Memorial Lectureship Award, American College of Rheumatology, 2004
Henry Christian Award for Excellence in Research, from the American Federation for Clinical Research, 1992
Arthritis Investigator of the Arthritis Foundation, 1984
Carol Nachman Prize in Rheumatology, 2007
Affiliations
Board of Directors, American College of Rheumatology, Chair
The Kunkel Society, Scientific Councilor
Clinical Immunology Society, Appointed Councilor
Editorial Appointments
Editorial Board, Lupus
Co-Editor, Arthritis and Rheumatism
Selected Publications
Girardi G, Yarilin D, Thurman JM, Holers VM, Salmon JE. Complement activation induces dysregulation of anglogenic factors and causes fetal rejection and growth restriction. J Exp Med 203: 2165-2175, 2006.
Roman M, Moeller E, Davis A, Paget SA, Crow MK, Lockshin MD, Sammaritano L, Devereux RB, Schwartz JE, Levine DM, Salmon JE. Preclinical carotid atherosclerosis in patients with rheumatoid arthritis: prevalence and associated factors. Ann Intern Med 144: 249-256, 2006.
Roman, MJ, Devereux RB, Schwartz JE, Lockshin MD Paget SA, Davis A, Crow MK, Sammaritano L, Levine D, Shanker B-A, Moeller E, Salmon JE. Arterial stiffness in chronic inflammatory diseases. Hypertension 46: 194-9, 2005.
Girardi G, Redecha PB, Salmon JE. Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation. Nat Med 10:1222-6, 2004.
Berman J, Girardi G, Salmon JE. TNF-a is a critical effector and a target for therapy in antiphosphospholipid antibody-induced pregnancy loss. J Immunol 174: 485-490, 2004.
Roman, MJ, Shanker B-A, Davis A, Lockshin M.D, Sammaritano L, Simantov R, Crow MK, Schwartz JE, Paget SA, Devereux RB, Salmon JE. Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosus. New Engl J Med 349: 2399-406, 2003.
Girardi G, Berman J, Redecha P, Spruce L, Thurman JM, Kraus D, Hollmann TJ, Casali P, Caroll MC, Wetsel RA, Lambris JD, Holers VM and Salmon JE. Complement C5a receptors and neutrophils mediate fetal injury in the antiphophospholipid syndrome. J Clin Invest 112: 1644-54, 2003.
Zuniga R, Markowitz GS, Arkachaisri T, Imperatore EA, D’Agati VD, Salmon JE. Identification of IgG subclasses and C-reactive protein in lupus nephritis: The relationship between the composition of immune deposits and Fc#RIIA alleles. Arthritis Rheum 2003; 48: 460-70
Holers VM, Girardi G, Mo L, Guthridge JM, Molina H, Pierangeli SS, Espinola R, Xiaowei LE, Mao D, Vialpando CG, Salmon JE. Complement C3 activation is required for anti-phospholipid antibody-induced fetal loss. J Exp Med 195:211-220, 2002.
Salmon JE, Pricop L: Human receptors for immunoglobulin G: Key elements in the pathogenesis of rheumatic disease. Arthritis Rheum 44: 739-750, 2001.
Salmon JE, Millard SS, Schachter LA, Arnett FC, Ginzler EM, Gourley MF, Ramsey-Goldman R, Kimberly RP: Fc#RIIA alleles are heritable risk factors for lupus nephritis in African Americans. J Clin Invest 97: 1348-1354, 1996.
Salmon JE, Millard SS, Brogle NL, Kimberly RP: Fcg receptor IIIb enhances Fcg receptor IIa function in an oxidant-dependent and allele-sensitive manner. J Clin Invest 1995; 95: 2877-2885.
For more publications, please see the
PubMed listing.
Selected Books/Chapters
Salmon JE, Kimberly RP, D’Agati V: Immunopathology of SLE. in: Rheumatology 3rd Edition, edited by MC Hochberg, AJ Silman, JS Smolen, ME Weinblatt, M Weisman. Mosby, London, pp 1297-1322, 2003; 4th edition, in press 2005.
Salmon JE: Mechanisms of Immune-mediated Injury. in: Cecil Textbook of Medicine (22nd edition), edited by L Goldman and D Ausiello, Saunders, Philadelphia, pp 223-227, 2004.
Salmon JE, Girardi G: The role of complement in the antiphospholipid syndrome. in: Current Directions in Autoimmunity, edited by G Tsokos. Karger, Basel, vol 7, pp 133-148, 2004.
Manzi S, Ahearn JM, Salmon JE. New Insights into Complement: A Mediator of Injury and Marker of Disease Activity in SLE. Lupus 13: 298-303, 2004.
Girardi G, Salmon JE. The Role of Complement in Antiphospholipid Antibody-Induced Pregnancy Loss and Thrombosis. in: Hughes Syndrome: Antiphospholipid Syndrome, 2nd edition, edited by M Khamashta, Springer-Verlag Ltd, London, in press.
Selected Presentations
Eric Bywaters Memorial Lectureship, Imperial College of London, UK, 2007
Dr. Jacob Probstein Endowed Lecture in Obstetrics and Gynecology, Washington University in St. Louis, 2004
Janice M. Wiles Memorial Lecture on SLE, University of Massachusetts, 2001
Kroc Visiting Professor, UCLA, 1997
Arthur DeGraff Lecture, New York University School of Medicine, 2007
Clinical Trials
Specialized Centers
Mary Kirkland Center for Lupus Research
